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However, these observations have not been replicated in nonhuman primates or humans and are believed to be a rodent phenomenon due to the higher density of GLP-1R on rodent C cells, so the responses obtained on rodents may not be relevant to primates (Samson and Garber, 2013
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For this new approach to be considered superior, it must demonstrate similar effectiveness in controlling binge eating and associated psychopathology while also achieving clinically meaningful and sustainable weight loss over time
J Inherit.Metab Dis 1-7-2008
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